OPEN SOURCE BIOLOGY
A Collective Movement to Neutralize COVID-19
HOW IT WORKS
Receive genetic sequences of the nanobodies within 24 hours of becoming an approved CCC19 Pledgor.
CCC19.ca's goal is to eliminate the barriers to blockbuster nanobodies and drive the development of scientific data, accurate
diagnostics, and efficacious therapeutics through cost-free licenses to all those that want to be part of the global movement.
We want to catalyze solutions for COVID-19 in an equitable model to complement the vast global effort underway and allow all stakeholders to benefit without leaving any group or patient behind.
The company offers a myriad of biologicals and biochemicals to Life Science researchers and clinicians providing products from virtually all of the world’s most renowned international manufacturers. Cedarlane provides a gateway to over two million global reagents. Customers have the advantage of freight consolidation, and the convenience and cost savings inherent within. Manufactured products include monoclonal and polyclonal antibodies, cell separation media, a complement for tissue typing, and highly characterized neuronal cell lines. Visit
Natural Products Canada (NPC) is the driving force behind Canada’s Natural Product Innovation Cluster–a strategic community of SMEs, research institutes, corporations, investors, government departments, and service providers who support the development and commercialization of naturally-derived products and technologies in health and life sciences, natural resources, agriculture and agri-food, and sustainable bioproducts. NPC has over 600 opportunities in its pipeline, has completed ten investments, and has already experienced two exits. Visit
NovoBind develops products that meet the growing global demand for increased food production without the use of antibiotics and antimicrobial chemicals. Their next-generation biologics target and neutralize devastating pathogenic bacteria, viruses, and parasites that cause $22 billion (USD) in aggregate annual loss to producers in the poultry, shrimp, and companion animal sectors. NovoBind is currently expanding its technology platform to address other sectors of food production, including crop health. Visit www.novobind.com,
SignalChem Lifesciences Corporation is a Canadian company focused on the research, development, and production of innovative and high-quality human recombinant cell signaling products. SignalChem strives to support scientists in academia, pharma, and biotech companies around the world by creating effective research tools to advance the basic research in life sciences and to facilitate the efforts in drug discovery and development.
Partners in Discovery and Innovation, law firm Wilson Sonsini has one of the largest life sciences practices in the world. For more than 60 years, our attorneys have worked closely with scientists, entrepreneurs, and investors who have helped develop new and innovative discoveries in nearly every field of medicine and healthcare, from genomics, immuno-oncology, and pharmaceuticals, to diagnostics and synthetic biology.
It is hypothesized that the best-known site for a single domain llama antibody (nanobody*) to neutralize SARS-CoV-2 is at the surface of the ACE2-receptor-binding domain (RBD) of the Spike protein (also known as S Protein). Nanobodies have previously been raised against the RBD of MERS-CoV. These antibodies protected mice prophylactically before exposure and therapeutically after exposure of MERS-CoV...
Tiwari, P.M., Vanover, D., Lindsay, K.E. et al. Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection. Nat Commun 9, 3999 (2018). https://doi.org/10.1038/s41467-018-06508-3
Zhao, G. et al. A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV. J. Virol. 92, e00837-18 (2018).
*Trademarked by Ablynx, otherwise known as single-domain antibodies, llama antibodies, VHH, VNAR
©2020 by Canadian Coalition for COVID-19